ABSTRACT
We report a case of Idiopathic non-lupus full-house nephropathy (NLFHN) in a 39-year-old male who had a full-house pattern of immunofluorescence study without overt systemic lupus erythematosus after a follow-up of more than 2 years. The incidence of detection of cases of NLFHN is increasing in native kidney biopsy and is critical to report as they have poor clinical outcomes. To the best of our knowledge, it is the first case of post-transplant renal biopsy and needs to be reported to plan the treatment protocol for such transplant patients.
ABSTRACT
Inherited epidermolysis bullosa (EB) is a family of diseases with blistering of skin and mucous membrane even with mild trauma. It has different subtypes based on the affected protein. Epidermolysis bullosa dystrophica (EBD) is associated with mutations in the COL7A1 gene encoding type VII collagen leading to the fragility of skin and mucosal membranes. EBD may be dominant or recessive. They should be distinguished because increased prevalence of SCC is associated with the recessive form. Here we are reporting a case at our hospital presented with various clinical features, history, clinical spectrum, renal biopsy and gene analysis giving appropriate diagnosis for the disorder. Treatment remains challenge. A multidisciplinary approach is needed for the effective management of EBD.